Located about three hours south of Santiago, the Valle du Maule is home to Chile’s only wholly American owned winery-Calina. From the vision of Kendall-Jackson founder Jess Jackson, Calina crafts top-notch wines including: Cabernet Sauvignon, Merlot, and a Chilean specialty, Carmenere. In Santiago, visit the downtown produce market and the Mercado Central, the oldest market in the city-one that specializes in seafood.